Business and Management

These capsules offer a reliable and effective packaging solution in the pharmaceutical industry. They are made from a variety of materials which come in a variety of sizes depending on your packaging needs. Capsules are small envelopes (cylindrical in shape) that seal drugs or other products.

The content can be powder, liquid, pellet, tablet or a mixture of any two products. You can browse online if you want to buy TES-5 semi-automatic capsule filling machine in the US.

In the modern pharmaceutical industry, capsules have become so popular that some tablets are even administered in capsule form. This is because the capsules are:

It is very tasteless and odorless so it is easy to manage

  • Easy to carry and handle
  • Cost effective
  • Contains a wide variety of products such as powders, pellets, or liquids.
  • Easy and convenient to fill

Capsule type

In order to meet the dynamic and safety requirements of the pharmaceutical industry, there are two main types of capsules in common use:

  • Soft gelatin capsules
  • Hard gelatin capsules

Soft gelatin capsules or soft gel are made of one ingredient as shown in the image below (all intact). The filling and production of soft gelatin capsules takes place simultaneously. This does not happen with hard gelatin capsules (you'll find out soon enough).

Hard gelatin capsules are usually used with automatic capsule filling machines. They are easier to fill and you can adapt to almost any capsule filling application.This can include fillers, pellets, tablets, or a mixture of the three. In most cases you will find that the body and hat are different colors.

Business and Management

Capsule filling with a nozzle dispenser (ND) has been studied extensively (Jones, 2001; Newton, 2012) and is one of the most important technologies used in the pharmaceutical industry today. The nozzles are available in sizes that fit the capsule diameter (from 00 to 5) and dispense a certain amount of powdered powder into the capsule.

The amount of powder that can be processed by the smallest nozzle (size 5) ranges from 40 mg to 80 mg (depending on the density of the powder formulation). You can also buy used capsule filling machine online.

Some new and promising drugs require powder handling in smaller amounts: 5 mg to 20 mg. The immediate solution is to expand the use of nozzle dispensers (by reducing the diameter of the nozzle) and use the functions already available for this technology: High-performance and highly automated weight control for quality control of each capsule.

However, this requires an understanding of the design space for smaller diameter nozzles and a review of the effect of process parameters and powder properties on capsule quality. The miniaturization of the nozzles is expected to affect the process performance and quality of the capsules.

In this study, Experimental Design (DOE) was used as part of the Quality by Design approach to investigate the effect of technological parameters and material properties of three small nozzles on fill weight and weight variability. Capsule filling machines (Labby, MG2) with one ND were used.